As compared with BA.2, the BA.2.12.1 subvariant has substitutions L452Q and S704L in its spike protein, and both BA.4 and BA.5 have additional changes. Substitutions L452Q, L452R, and F486V are in the ...
The mRNA-1273 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicited high neutralizing-antibody titers in phase 1 trial participants 1,2 and has been shown to be ...