LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

The data showed that roughly 65% of the cells in the oxygenated devices remained viable compared to roughly 20% in control devices.

CRISPR-Cas9 technology is used to knock out or modify DNA in research mice to study disease phenotypes and develop new treatments. CRISPR mice and rats are offered by Charles River, which uses genetic ...

Animal models have long shaped how biomedical research is conducted. They have influenced how diseases are studied, how risks are assessed, and how potential treatments move from early discovery ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

Researchers’ interest in marmosets as animal models has driven a sharp increase in demand for them. Presenters discussed the context of wild marmoset populations, challenges and opportunities for ...

I recently read a highly-detailed, comprehensive, science-based report called The Research Modernization Deal 2021. It unambiguously shows that numerous experiments on nonhuman animals (animals) fail ...

Phasing out animal testing in preclinical drug trials in favor of unvalidated alternate methodologies could ultimately backfire and raise safety and effectiveness concerns, says Sara Gerke, the ...

Animal testing for new drugs is being phased out because of advances made in artificial intelligence (AI), the UK’s medicines regulator has said. In an announcement on Tuesday, the Medicines and ...