B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

Lymph nodes are key control centers in the immune system and play an important role in defending the body against infections ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

A groundbreaking study by Vanderbilt Health researchers has revealed a greater, detrimental role for B lymphocytes, or B cells, in the progression of Type 1 diabetes (T1D). B cells are immune cells ...

Scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two ...

Immunity is orchestrated by two responses referred to as the innate and adaptive immune systems. Each system works to ...