The gut microbiota have a known role in modulating gut immune homeostasis. Largely, through the development and function of host immune cells, including T helper cells expressing interleukin-17A. It ...

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect ...

Primary bile acids are produced by the liver and released into the gut, where diverse groups of bacteria work together to modify their chemical structures. Researchers suspected these gut microbial ...

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has made an incredible impact on treating cancers in many different organ ...

Researchers have used a mouse model to show that infections in the intestine can change the composition of bile, a fluid that is generated in the liver and is crucial to digestion. Bile aids in the ...

The image depicts gut microbes producing secondary bile acids to support the host’s immune defense against cancer. Microbiota-derived bile acids (shown in light green) blocked the androgen receptor ...