Everyday Health on MSN

C3G/IC-MPGN progression: Can new C3 inhibitors stop the path to dialysis?

For years, patients with C3G and IC-MPGN had few options to stop the progression toward kidney failure. Now a new class of ...
Monthly Prescribing Reference

Pegcetacoplan Beneficial for C3 Glomerulopathy, Immune-Complex MPGN

The change in proteinuria was significantly greater with pegcetacoplan than placebo, representing a 68.1% relative reduction vs placebo. HealthDay News — Among patients with C3 glomerulopathy or ...
Everyday Health

What Are C3 Glomerulopathy (C3G) and Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)?

C3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are rare and progressive kidney diseases, caused by problems in the immune system. They are two distinct ...
The New England Journal of Medicine

Pegcetacoplan in C3 Glomerulopathy and Immune-Complex MPGN

This trial of pegcetacoplan, a C3 and C3b inhibitor, in patients with C3 glomerulopathy or primary immune-complex membranoproliferative glomerulonephritis showed that the drug significantly reduced ...