As many as 1 in 4 cancers are driven by mutations in the SWI/SNF chromatin-remodeling complex, which controls access to DNA.

The intricate interplay between malignant cells and the immune system is increasingly underscored by the role of CD200, a widely expressed membrane glycoprotein. By engaging with its inhibitory ...

Bcl-3 is an atypical member of the IκB family that plays a critical role in modulating the NF‐κB transcriptional programme. Unlike classical inhibitors that sequester NF‐κB in the cytoplasm, Bcl-3 ...

Fox Chase researchers use 3D genomic testing to improve lymphoma and sarcoma diagnosis and treatment by revealing tumor cell ...

Cancer cells are metabolic opportunists, bending every pathway to fuel unchecked growth. Now UCLA scientists show that a single protein—Insulin-like Growth Factor 2 mRNA-Binding Protein 3 ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

New York, NY—In the Great Hall of the Cunard Building, deep in Lower Manhattan, members of the Cancer Research Institute (CRI), a nonprofit that supports the discovery and development of cancer ...

University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene regulation networks with applications in cancer survival analysis. The tool, ...

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it. Professor Néstor Oviedo, ...

Correlation between the number of circulating epithelial tumor cells (CETCs/CTCs) and circulating tumor DNA (ctDNA) in patients with colorectal cancer. This is an ASCO Meeting Abstract from the 2025 ...

A case in which a sperm donor was later found to be carrying a cancer-causing pathogenic variant in his gametes has highlighted the problems of regulating gamete donation at European and international ...