In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the ...

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part ...

Bioengineers have developed a platform that accurately replicates conditions cancer cells encounter while traveling through ...

Neuronal death is the indisputable endgame of Alzheimer’s disease, but what does the killing, and how? To try to solve the mystery, researchers have staged increasingly complex crime scenes in ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

The Advanced Cell Engineering and 3D Models (ACE-3M) Core provides established services offered previously by AIM and C-BASS cores plus new expanded capabilities for tumor organoids grown in 3D ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...

3D cell cultures are no longer a futuristic idea. They’re already reshaping how we study diseases like cancer, offering more realistic models of how cells behave in the body. But despite their ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...