Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies. Researchers led by ...

Tissue makeup depends on the local cellular microenvironment. Spatial single-cell genomics enables scalable and unbiased interrogation of these interactions. Here we introduce Nicheformer, a ...

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...

aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

Yusuf Roohani, PhD, machine learning group lead at the Arc Institute, is among a team of researchers training artificial intelligence (AI) models with transcriptome data to predict how cell gene ...

The interplay between transcription factors (TFs) and regulatory elements (REs) drives gene transcription, forming gene regulatory networks (GRNs). Advances in single-cell technologies now enable ...

During early development, tissues and organs begin to bloom through the shifting, splitting, and growing of many thousands of cells. A team of MIT engineers has now developed a way to predict, minute ...

Five years ago, scientists watched in wonder as synthetic bacteria grew and split into daughter cells. The bacteria’s extremely stripped-down genome still supported its entire life cycle. It was a ...