Scientists have identified prematurely aged astrocytes in the brains of Alzheimer’s patients, particularly those with the APOE4 risk gene. Their findings suggest that cellular senescence in these ...

Biomolecular condensates were long believed to be simple liquid blobs inside cells. Researchers have now uncovered that some are actually supported by fine protein filaments forming an internal ...

Cells were long believed to safeguard nuclear contents, releasing them only during cell death. Extracellular DNA was thought ...

In the rapidly evolving field of drug discovery, single-cell analysis has become an invaluable tool for understanding cellular heterogeneity and molecular pathways. However, traditional single-cell ...

The field of cellular neuroscience continues to reveal the intricate regulation of neural and glial cell function by water and ion channels, transporters, ...

Single-cell functional analysis enables scientists to examine the unique characteristics of each cell within organs, tissues, and cell cultures. Unlike bulk-cell analysis, single-cell analysis allows ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Single-cell analysis is a ubiquitous laboratory technique that allows researchers to probe the myriad biomolecular states of cells. Single-cell assays can reveal gene and protein expression patterns, ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

* Reeve-Irvine Research Center, and Departments of Anatomy/Neurobiology and Neurobiology and Behavior, College of Medicine, University of California, Irvine, CA 92697; and ‡ Department of Neuroscience ...