MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a ...

Scientists from the University of Sheffield, the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have helped solve a decade-long ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

Researchers revealed a CRISPR system that activates gene expression rather than cutting DNA, using RNA-guided targeting. The ...