The researchers unravel the exact mechanism of how developmentally active enhancers become repurposed in a tumor context and show the relevance of this repurposing event for cancer. University of ...

The images show the abdomen of flies in which a specific enhancer region has been modified. Depending on how much and which part of the region is modified, different areas of the pigment pattern ...

When the Nanog gene (green region) is inactive, one of the three enhancer regions is spatially far away. When active, the same enhancer region makes close contact, interacting with the other enhancers ...

University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called ...