Researchers led by Davide Incarnato at the University of Groningen have demonstrated that the FDA-approved cancer drug ...

This study illustrates how persistent mRNA rG4 structures induce ribosome pausing and collisions, leading to proteostasis collapse in senescent cells. The RNA helicase DHX9 acts as a key regulator, ...

Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these ...

ADAR1 Zβ bound to a G-quadruplex. RNA editing by ADAR1 improves the performance of the DNA repair protein NEIL1. Recoding is likely facilitated by the G-quadruplex that localizes ADAR1 to this site.

This study is led by Dr. Xiaogang Qu (Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences) ...

Researchers from Aarhus University and the Italian Institute of Technology have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...