DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Scientists looked at multiple techniques used to measure the modified viruses deployed in some gene therapy research and treatments. One technique, known as SEC-MALS, was the most precise and accurate ...

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and epigenetic state. By analyzing thousands of sequences, the method showed that ...

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently ...

Early results from a study of newborn screening methods show that DNA analysis picks up many more preventable or treatable serious health conditions than standard newborn screening and is favored by ...

The authors received funding for this work from the now defunded Biological Heritage National Science Challenge. University of Auckland, Waipapa Taumata Rau and University of Otago provide funding as ...

Some gene therapy treatments use modified adeno-associated viruses (AAVs) like the one shown here to deliver therapeutic genetic material into a patient’s cells. In a finding with implications for one ...