Lung Cancer Master Protocol (Lung-MAP), a public-private partnership, established infrastructure for conducting a biomarker-driven master protocol in molecularly targeted therapies. We compared ...

Why do you believe master protocols are so important to the future of clinical research? A master protocol approach can provide inferential benefits and operational efficiency. Clinical development is ...

Timing of Adjuvant Chemotherapy After Gastrectomy in Patients With Stage II to III Gastric Cancer: A Target Trial Emulation Study Master protocols represent transformations, enabling multiple ...

SJ: Amgen has been doing innovative trial designs for well over 5-6 years. We incorporate innovative designs in probably at least 70-80% of our protocols. The therapeutic area where we use them the ...

To accelerate drug development targeting the pandemic, the FDA issued final guidance May 17 on master protocols for drugs intended to prevent or treat COVID-19 infections. Although the guidance is ...