Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis (Mtb), which causes tuberculosis featuring lung ...

A new study, "Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein" published in Biochemistry, provides key insights into how bacterial cAMP receptor proteins (CRPs) ...

In 2021, a global tuberculosis vaccine research and development roadmap proposed a series of actions to accelerate the development of new, effective, and affordable vaccines that are urgently needed ...

Prevention of drug-resistant tuberculosis is a global health priority. However, trials evaluating the effectiveness of treating Mycobacterium tuberculosis infection among contacts of persons with drug ...

However, the researchers found that, unlike M. tuberculosis, M. spongiae does not cause disease in mice, making it non-virulent. The University of Melbourne's Dr Sacha Pidot, a Laboratory Head at the ...

Working toward more effective tuberculosis (TB) vaccines, researchers have developed two strains of mycobacteria with 'kill switches' that can be triggered to stop the bacteria after they activate an ...

Untreated tuberculosis may result in several long-term complications, such as permanent lung damage. It’s vital for the condition to be treated early to prevent the infection from traveling to other ...