A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...
The database of 200 million protein-structure predictions now includes homodimers, adding new biological relevance.
A new collaboration between EMBL's European Bioinformatics Institute (EMBL-EBI), Google DeepMind, NVIDIA, and Seoul National ...
Four-way collaboration brings together world-leading AI and biological expertise to make AI-predicted protein complex ...
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Structural biology is shifting from predicting protein shapes to uncovering broader organizational rules; AI tools like AlphaFold have made large-scale protein structure data far ...
Cryo-EM reconstructions of the human ATR–ATRIP complex show how clinical small-molecule inhibitors like VE-822 and RP-3500 bind to and inhibit ATR activity. A research team led by Prof. Gang Cai and ...
Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...
The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
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