Hierarchical spatial organization is ubiquitous in tissue and organ biology. Systematic, high-dimensional phenotypic measurements of this organization, generated through experimental tools such as ...
The advancement of single-cell RNA sequencing and spatial transcriptomics has enabled the inference of cellular interactions in a tissue microenvironment. Despite advances in cell-cell interaction ...
Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...
Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...