Identifying cell–cell interactions from imaging-based spatial transcriptomics suffers from limited gene panels. A new self-supervised graph transformer-based method can resolve spatial ...

Celcomen leverages a mathematical causality framework to disentangle intra- and inter-cellular gene regulation programs in spatial transcriptomics data through a generative graph neural network. It is ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Since its inception, spatial biology has proven a revolutionary frontier in life science research. However, there is still plenty of room for growth in the systems we use to conduct spatial biology ...

Why do so many promising drugs fail? This article explores how spatial multiomics reveals hidden cell interactions, helping ...

Spatial biology offers researchers a comprehensive view and understanding of complex tissues, capturing details about their organization and structure that inform how they function. This ability to ...

A new study constructs the first 3D single-cell brain atlas of the lamprey, uncovering the 450-million-year-old molecular blueprint of vertebrates.

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder ...

With a trio of partnership announcements this month, 10x Genomics has signaled it is looking beyond its traditional focus on research tools for academic, government, and industry customers, by ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder ...

Spatial analyses uncovered how different tumor regions interact with immune cells and respond to therapies, offering a new ...