In aggressive lymphomas, inflammatory messengers reprogram the "conductors" of the immune system, causing lymph nodes ...

A new study maps the organisation of immune and stromal cells in lymph nodes and shows how loss of this organisation affects ...

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

Lymph nodes are key control centers in the immune system and play an important role in defending the body against infections ...

Findings show lymphoma reshapes stromal cell signaling, replacing structural chemokines with inflammatory signals, leading to ...

Architectural principles of lymphoma-induced lymph node tissue remodeling” F. Czernilofzky, A. Mathoiudaki, L. Jopp-Saile, R. Lutz, D. Vonficht, X. Wang, C. Schiederjohann, H. Voehringer, T. Roider, M ...

In almost all solid tumors—i.e. cancers with a solid tissue structure—the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease. Lymph node ...

Tumors, such as melanoma, release nanovesicles called exosomes (gray) that travel and lodge in the lymph nodes. There they corrupt the behavior of lymph cells. The lymphatic vessels (green) branch out ...

A new method to keep human lymph node tissue alive and functioning outside the body for several days could give researchers a much clearer view of how our immune system responds to infections, ...

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to ...