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The axonal cytoskeleton and other components. The structural support provided by spectrin and actin near the cell membrane, which itself is packed with channel proteins. There are tracks formed by microtubules, and motor proteins utilize them to move vesicles. This visualization highlights only a few key features; a real axon is far more complex, housing essential structures like mitochondria and various other cellular components. | Ribosome Studio
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Exciting new research from Drs. Stéphane Vassilopoulos, Christophe Leterrier, and colleagues appearing in Science sheds light on a novel regulatory mechanism of endocytosis in the axon 🧠 🔬 By combining #SuperResolution optical #Microscopy and platinum replica electron microscopy #EM they reveal the details of clathrin-mediated endocytosis in the axon shaft and axonal initial segment (AIS), showing how AIS actin-spectrin scaffolding forms exclusion zones where unusually stable clathrin-coated p
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